We present the development of a new algorithm which combines state-of-the-art energy-dispersive x-ray (EDX) spectroscopy theory and a suitable machine learning formulation for the hyperspectral unmixing of scanning transmission electron microscope EDX spectrum images.The algorithm is based on non-negative matrix factorization (NMF) incorporating a

The review presents, as the classical data on the mechanism of action of metabolic cytoprotector trimetazidine in click here acute ischemia/reperfusion injury associated with a partial inhibition of the oxidation of long chain fatty acids and increased metabolism of pyruvate, as well as new concepts of reducing the level of oxidative stress, reduct

Introduction: Coccidioidal meningitis (CM) is the most lethal form of disseminated coccidioidomycosis.Current guidelines recommend fluconazole as initial therapy but there has been a paucity of data regarding failure of fluconazole and optimal fluconazole dosage in the treatment of CM.We conducted this study to understand risk peperomia double duty

Surface proteins of Gram-positive pathogens are key determinants of virulence that substantially shape host-microbe interactions.Specifically, these proteins mediate host invasion and pathogen transmission, drive the acquisition of heme-iron from hemoproteins, and subvert innate and adaptive immune cell responses to push bacterial survival and path